Mariana Castanheira Selected Research

Ceftaroline

1/2023	Update on the in vitro activity of ceftaroline against Staphylococcus aureus from United States (US) medical centers stratified by infection type (2018-2020).
5/2017	Ceftaroline Activity Tested Against Bacterial Isolates Causing Community-acquired Respiratory Tract Infections and Skin and Skin Structure Infections in Pediatric Patients From United States Hospitals: 2012-2014.
5/2015	Antimicrobial activity of ceftaroline tested against bacterial isolates causing respiratory tract and skin and skin structure infections in US medical centers in 2013.
8/2014	Activity of ceftaroline and comparator agents tested against contemporary Gram-positive and -negative (2011) isolates collected in Europe, Turkey, and Israel.
9/2012	Activity of ceftaroline-avibactam tested against Gram-negative organism populations, including strains expressing one or more β-lactamases and methicillin-resistant Staphylococcus aureus carrying various staphylococcal cassette chromosome mec types.
9/2012	In vitro activity of ceftaroline against multidrug-resistant Staphylococcus aureus and Streptococcus pneumoniae: a review of published studies and the AWARE Surveillance Program (2008-2010).
1/2012	Pharmacodynamics of β-lactamase inhibition by NXL104 in combination with ceftaroline: examining organisms with multiple types of β-lactamases.

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Mariana Castanheira Research Topics

Disease

75	Infections 02/2024 - 01/2003
15	Urinary Tract Infections (Urinary Tract Infection) 01/2024 - 12/2015
13	Pneumonia (Pneumonitis) 04/2023 - 08/2014
11	Sepsis (Septicemia) 04/2023 - 11/2010
9	Bacterial Pneumonia 01/2022 - 06/2010
6	Intraabdominal Infections 01/2022 - 12/2015
6	Invasive Fungal Infections 01/2022 - 10/2014
5	Respiratory Tract Infections (Respiratory Tract Infection) 01/2018 - 04/2010
4	Mycoses (Diseases, Fungus) 01/2024 - 10/2016
4	Ventilator-Associated Pneumonia 01/2021 - 07/2015
3	Invasive Candidiasis 03/2024 - 11/2012
3	Candidemia 03/2024 - 06/2014
3	Cross Infection (Nosocomial Infection) 01/2022 - 01/2017
3	Candidiasis (Moniliasis) 01/2020 - 01/2016
3	Neoplasms (Cancer) 01/2018 - 10/2016
2	Pyelonephritis 01/2023 - 08/2018
2	Bacterial Infections (Bacterial Infection) 01/2022 - 01/2017
2	Soft Tissue Infections 12/2021 - 08/2014
2	Cystic Fibrosis (Mucoviscidosis) 09/2021 - 01/2018
2	Healthcare-Associated Pneumonia 01/2021 - 01/2020
2	Thrombosis (Thrombus) 01/2019 - 04/2018
2	Osteomyelitis 04/2018 - 06/2017
1	Gonorrhea 01/2024
1	Mucormycosis 02/2023
1	Community-Acquired Infections 01/2022
1	Bacteremia 01/2019
1	Persistent Infection 01/2019
1	Abscess 01/2019
1	Subphrenic Abscess (Subdiaphragmatic Abscess) 01/2019

Drug/Important Bio-Agent (IBA)

19	ceftazidime drug combination avibactamIBA 04/2023 - 01/2015
16	tazobactam drug combination ceftolozaneIBA 04/2023 - 09/2013
13	EchinocandinsIBA 03/2024 - 01/2011
11	avibactamIBA 02/2024 - 01/2012
11	Carbapenems (Carbapenem Antibiotics)IBA 02/2024 - 01/2007
9	LactamsIBA 02/2022 - 12/2015
8	Meropenem (Merrem)FDA LinkGeneric 10/2023 - 08/2016
7	RezafunginIBA 03/2024 - 10/2016
7	Aztreonam FDA LinkGeneric 02/2024 - 10/2020
7	Ceftaroline FDA Link 01/2023 - 01/2012
7	meropenem and vaborbactamIBA 01/2023 - 01/2016
6	Cephalosporins (Cephalosporin Antibiotics)IBA 01/2022 - 09/2010
5	Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric 04/2023 - 08/2016
5	dalbavancinIBA 05/2022 - 01/2016
5	oritavancinIBA 01/2022 - 12/2016
5	solithromycinIBA 01/2011 - 04/2010
4	Caspofungin (Cancidas)FDA Link 03/2024 - 11/2012
4	Tazobactam FDA LinkGeneric 03/2022 - 06/2013
4	Antifungal AgentsIBA 11/2021 - 07/2011
3	Ceftibuten (Cedax)FDA Link 04/2023 - 01/2022
3	Cefepime (Maxipime)FDA LinkGeneric 03/2022 - 09/2010
3	Linezolid (Zyvox)FDA Link 01/2022 - 06/2008
3	AzolesIBA 06/2021 - 01/2011
3	FluoroquinolonesIBA 01/2021 - 01/2017
3	Ceftazidime (Fortum)FDA LinkGeneric 01/2019 - 09/2010
3	carbapenemaseIBA 01/2019 - 01/2016
3	beta-Lactamases (beta-Lactamase)IBA 04/2014 - 09/2008
2	gepotidacinIBA 01/2024 - 01/2023
2	isavuconazoleIBA 11/2023 - 02/2023
2	Minocycline (Cyclops)FDA LinkGeneric 11/2023 - 10/2021
2	Anti-Infective Agents (Microbicides)IBA 10/2023 - 12/2014
2	Voriconazole (Vfend)FDA LinkGeneric 10/2023 - 04/2016
2	Imipenem FDA Link 04/2023 - 12/2021
2	relebactamIBA 04/2023 - 12/2021
2	tebipenemIBA 01/2023 - 10/2022
2	tedizolidIBA 01/2022 - 07/2019
2	MacrolidesIBA 01/2021 - 01/2017
2	Fluconazole (Zonal)FDA LinkGeneric 01/2020 - 11/2010
2	plazomicinIBA 05/2019 - 01/2018
2	Third Generation CephalosporinsIBA 01/2018 - 01/2003
2	cefepime-zidebactamIBA 01/2017 - 01/2017
2	EnzymesIBA 01/2015 - 09/2012
2	Fusidic Acid (Fucithalmic)IBA 06/2011 - 03/2010
1	APX001AIBA 01/2024
1	Topoisomerase InhibitorsIBA 01/2024
1	Amphotericin B (Amphotericin)FDA LinkGeneric 10/2023
1	posaconazole FDA Link 10/2023
1	Itraconazole (Sporanox)FDA LinkGeneric 10/2023
1	AminoglycosidesIBA 02/2023
1	sulopenemIBA 01/2023
1	ProdrugsIBA 01/2023
1	SiderophoresIBA 01/2022
1	CefiderocolIBA 01/2022
1	Daptomycin FDA Link 01/2022
1	Tetracycline (Achromycin)FDA LinkGeneric 01/2022
1	kbp-7072IBA 01/2022
1	LincosamidesIBA 01/2021
1	Methicillin (Metin)FDA Link 01/2021
1	Clindamycin (Cleocin)FDA LinkGeneric 01/2021
1	CoagulaseIBA 07/2019
1	Amikacin (A.M.K)FDA LinkGeneric 10/2018
1	Gentamicins (Gentamicin)FDA LinkGeneric 09/2018
1	Levofloxacin (Levaquin)FDA Link 09/2018
1	Colistin (Coly-Mycin)FDA Link 09/2018
1	Doripenem FDA Link 08/2018
1	Anti-Bacterial Agents (Antibiotics)IBA 04/2018

Therapy/Procedure

10	Therapeutics 01/2023 - 06/2011
5	Mechanical Ventilators (Ventilator) 01/2022 - 01/2018
1	Salvage Therapy 01/2019
1	Liver Transplantation 01/2019
1	Catheters 04/2018